AHCC07
Explore the PLANet Study (AHCC 07), a multi-centre Asia-Pacific research effort using precision medicine to improve liver cancer outcomes.
Trial summary of AHCC 07
AHCC 07 | Precision Medicine in Liver Cancer across an Asia-Pacific Network (The PLANet Study) (NCT03267641) |
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Status | Updated data as of June 2025 showed that 187 of 277 patients have reached the study end-points (as defined by recurrence or death, or completion of 3 years follow-up from date of surgery). Two main publications in Cell (DOI: 10.1016/j.cell.2020.08.040) and Nature Communications (DOI: 10.1038/s41467-020-20171-7). Patent:
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Contributing Principal | Malaysia Yoong Boon Koon (University Malaya Medical Center) Philippines Maria Vanessa H. de Villa (The Medical City) Singapore Pierce Chow (National Cancer Centre), Glenn Bonney (National University Hospital), Brian Goh (Singapore General Hospital) Thailand Rawisak Chanwat (National Cancer Institute) United States of America Sabino Zani Jr (Duke University School of Medicine) |
Thematic Principal Investigators | Theme: Genomic evolution in HCC and the discovery of novel drug targets Name: Zhai Weiwei Designation: Senior Research Scientist Institution: Genome Institute of Singapore Theme: Translational Immunomics: Immune-phenotyping, monitoring and discovery of novel immunotherapies Name: Salvatore Albani Designation: Director Institution: SingHealth Translational Immunology and Inflammation Centre Theme: Clinical Trajectory and Translational Therapeutics Name: Pierce Chow Designation: Senior Consultant Institution: National Cancer Centre |
Protocol Chair | Pierce Chow |