Cancer

SCRI has a broad experience in the fast growing therapeutic field of haematology and oncology

A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma

Tan, T.J., Ang, W.X.G., Wang, WW. Et al. A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma. Nat Commun 13, 6453 (2022). https://doi.org/10.1038/s41467-022-33834-4

Psychometric Properties of the Breast Cancer Screening Beliefs Questionnaire Among Women of Indian Ethnicity Living in Australia

Kwok C, Pillay R, Lee CF. Cancer Nurs. 2015

Breast Cancer Screening Beliefs Questionnaire: Psychometric properties assessment of the Arabic version

Kwok C, Endrawes G, Lee CF. Eur J Oncol Nurs. 2016 Feb;20:42-8.

Mapping and direct valuation: do they give equivalent EQ-5D-5L index scores?

Luo N, Cheung YB, Ng R, Lee CF. Health Qual Life Outcomes. 2015;13(1):166.

On developing a pragmatic strategy for clinical trials: A case study of hepatocellular carcinoma

Gandhi M, Tan SB, Chung Yaw Fui A, Machin D. Contemp Clin Trials. 2015 Jul;43:252-9.

Summary scores captured changes in subjects’ QoL as measured by the multiple scales of the EORTC QLQ-C30

Phillips R, Gandhi M, Cheung YB, Findlay MP, Win KM, Hai HH, Yang JM, Lobo RR, Soo KC, Chow PK. J Clin Epidemiol. 2015 Mar 3 (ePub).

Cost-effectiveness analysis of liver resection versus transplantation for early hepatocellular carcinoma within the Milan criteria

Lim KC, Wang VW, Siddiqui FJ, Shi LM, Chan SY, Oh HC, Tan SB, Chow PK. Hepatology 2015, 61(1):227-237.

Patient-reported outcomes are associated with patient-oncologist agreement of performance status in a multi-ethnic asian population

Lee CF, Ng R, Luo N, Cheung YB. Supportive Care in Cancer 2014, 22 (12): 3201-3208.

Multicenter phase II study of sequential radioembolization-Sorafenib therapy for inoperable hepatocellular carcinoma

Chow PKH, Poon DYH, Khin MW, Singh H, Han HS, Goh ASW, Choo SP, Lai HK, Lo RHG, Tay KH, Lim TG, Gandhi M, Tan SB, Soo KC. PLOS ONE 2014, 9(3): e90909.

The English and Chinese versions of the five-level EuroQoL Group’s five-dimension questionnaire (EQ-5D) were valid and reliable and provided comparable scores in Asian breast cancer patients

Lee CF, Ng R, Luo N, Wong NS, Yap YS, Lo SK et al. Support Care Cancer 2013;21(1):201-9.

Comparison of the measurement properties between a short and generic instrument, the 5-level EuroQoL Group’s 5-dimension (EQ-5D-5L) questionnaire, and a longer and disease-specific instrument, the Functional Assessment of Cancer Therapy-Breast (FACT-B), in Asian breast cancer patients

Lee CF, Luo N, Ng R, Wong NS, Yap YS, Lo SK et al. Qual Life Res 2013;22(7):1745-51.

Measurement properties of the eight-item abbreviated functional assessment of cancer therapy–breast symptom index and comparison with its 37-item parent measure

Lee CF, Ng R, Wong NS, Luo N, Yap YS et al. J Pain Symptom Manage 2013;45(4):782-91.

The Functional Living Index-Cancer is a reliable and valid instrument in Chinese cancer patients

Fong DY, Lee AH, Tung SY, Wong JY, Chan YM, Goh CR, Cheung YB. Qual Life Res. 2014 Feb;23(1):311-6.

Adjuvant hepatic intra-arterial Iodine-131-Lipiodol following curative resection of hepatocellular carcinoma: A prospective randomized trial

Chung AY, Ooi LL, Machin D, Tan SB, Goh BK, Wong JS et al. World Journal of Surgery 2013;37(6):1356-61.

Induction chemoradiation is not superior to induction chemotherapy alone in stage IIIA lung cancer

Shah AA, Berry MF, Tzao C, Gandhi M, Worni M, Pietrobon R, D’Amico TA. Ann Thorac Surg. 2012;93(6):1807-12.

Systematic review of outcomes of liver resection for early hepatocellular carcinoma within the Milan criteria

Lim KC, Chow PKH, Allen JC, Siddiqui FJ, Chan ESY, Tan SB. Br J Surg. 2012;99(12):1622-9.

Lower dose dexamethasone/thalidomide and zoledronic acid every 3 weeks in previously untreated multiple myeloma

Teoh G, Chen Y, Kim K, Srivastava A, Pai VR, Yoon SS, Suh C, Kim YK. Clin Lymphoma Myeloma Leuk. 2012;12(2):118-26.

Randomised double-blind trial of megestrol acetate vs placebo in treatment-naive advanced hepatocellular carcinoma.

Chow PK, Machin D, Chen Y, Zhang X, Win KM, Hoang HH, Nguyen BD, Jin MY, Lobo R, Findlay M, Lim CH, Tan SB, Gandhi M, Soo KC; Asia-Pacific Hepatocellular Carcinoma Trials Group. Br J Cancer. 2011;105(7):945-52.

Measurement properties of the English and Chinese versions of the Functional Assessment of Cancer Therapy-Breast (FACT-B) in Asian breast cancer patients

Ng R, Lee CF, Wong NS, Luo N, Yap YS, Lo SK, Chia J, Yee A, Krishna L, Goh C, Cheung YB. Breast Cancer Res Treat. 2012;131(2):619-25.

Microvascular invasion is a better predictor of tumor recurrence and overall survival following surgical resection for hepatocellular carcinoma compared to the Milan criteria.

Lim KC, Chow PKH, Allen JC, Chia GS, Lim MS, Cheow PC, Chung AYF, Ooi LLP, Tan SB. Ann Surg. 2011;254(1):108-13.

Multicenter study of comparative outcomes of hematopoietic stem cell transplant for peripheral T cell lymphoma and natural killer/T-cell lymphoma

Hwang WYK, Koh LP, Lim ST, Linn YC, Loh YS, Koh MBC, Diong CP, Lee JJ, Zhang XH, Rajgor D, Gandhi M, Shah A, Goh YT. Leuk Lymphoma. 2011 Jul;52(7):1382-6.

Germline variation controls the architecture of somatic alterations in tumors

Dworkin AM, Ridd K, Bautista D, Allain DC, Iwenofu OH, Roy R, Bastian BC, Toland AE. PLoS Genet. 2010; 6(9): e1001136.

Phase II clinical trial designs in Oncology: Are we hitting the target?

Ang MK, Tan SB, Lim DWT. Expert Rev Anticancer Ther. 2010;10(3):427-38.

VKORC1 diplotype-derived dosing model to explain variability in warfarin dose requirements in Asian patients

Sandanaraj E, Lal S, Cheung YB, Xiang X, Kong MC, Lee LH, Ooi LL, Chowbay B. Drug Metabolism and Pharmacokinetics. 2009;24(4): 365-375.

Measurement properties of the Chinese version of functional assessment of cancer therapy-general In a Singapore population

Cheung YB, Goh C, Wee J, Khoo KS, Thumboo J. Ann Acad Med Singapore. 2009;38(3):225-9.

Mapping the English and Chinese versions of functional assessment of cancer therapy-general to the EQ-5D utility Index

Cheung YB, Thumboo J, Gao F, Ng GY, Pang G, Koo WH, Sethi VK, Wee J, Goh C. Value Health. 2008; 17(9):1173-81.