ACSIKS (Multi-centre Ophthalmology Study)

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The Asia Cornea Society Infectious Keratitis Study (ACSIKS) is a three-year, multi-centre, prospective and observational study of infectious keratitis cases in 30 sites spanning eight different Asian countries: India, China, Japan, South Korea, Taiwan, Thailand, Philippines and Singapore. The total number of recruited subjects exceeded 6,500 and the first phase of the project has been successfully completed.

The SCRI Data Management Team performs remote monitoring for the large-scale ACSIKS study by examining a variety of datasets to uncover hidden data patterns, correlations, and trends including data entry preferences and other useful operational information. These trial analytical findings can lead to more effective ways of identifying and securing data quality and improved operational efficiency.

The Data Management Team developed a customised database for the ACSIKS Study that is simple and user-friendly enough to allow all 30 sites to enter diverse study data with ease. It also programmes automated system checks to ensure data consistency and streamline data cleaning, and integrates interactive query management for effective communication with the sites to ensure the quality and integrity of data are closely monitored in a central monitoring system. In addition, the Team generates monthly data metrics to the Project Management Team for project progress updates.

The Data Management Team also addressed the PI’s needs to generate special data listings and reports for presentation at the Asia Cornea Society Conference. The Data Management Team works closely with the Biostatisticians to effectively merge multiple data tables to produce clinically relevant datasets.