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PhD-level research staff members with faculty appointments in local and overseas universities develop new research methods to handle new problems that arise from time to time. Major areas and some scientific outputs include: |
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- Analysis of time-to-event and disease incidence
Cheung YB, Xu Y, Tan SH, et al. Estimation of intervention effects using first or multiple episodes in clinical trials: The Andersen-Gill model re-examined. Statistics in Medicine 2010; 29: 328-336.
Xu Y, Cheung YB, Lam KF, et al. A simple approach to the estimation of incidence rate difference. American Journal of Epidemiology 2010; in press.
- Biomarkers in clinical trials
Chow SC, Lu Q, Tse SK, et al. Statistical methods for assessment of biosimilarity using biomarker data. Journal of Biopharmaceutical Statistics 2010; 20: 90-105.
Li W, Qu Y. Adjustment for the measurement error in evaluating biomarkers. Statistics in Medicine 2010; in press.
- Clinical trial designs
Lu Q, Tse SK, Chow SC. Analysis of time-to-event data under a two-stage survival adaptive design in clinical trials. Journal of Biopharmaceutical Statistics 2010; 20: 705-19.
Tan SB, Wee J, Wong HB, et al. Can external and subjective information ever be used to reduce the size of randomized controlled trials? Contemporary Clinical Trials 2008; 29: 211-219.
- Quality of life and outcomes research
Cheung YB, Goh C, Thumboo J, et al. Variability and sample size requirements of quality of life measures: A randomised study of three major questionnaires. Journal of Clinical Oncology 2005; 23: 4936-44.
Cheung YB, Thumboo J, Gao F, et al. Mapping the English and Chinese versions of the Functional Assessment of Cancer Therapy–General to the EQ-5D utility index. Value in Health 2010; in press.
