Research Interests:
- Depressive Disorders
- Therapeutic Trials
- Biomarkers
- Treatment Guidelines
Selected Publications:
Fava M, Rush AJ, Alpert JE, et al. Difference in treatment outcome in outpatients with anxious versus nonanxious depression: A STAR*D report. Am J Psychiatry, 165:342-351, 2008.
Rush, A.J., Wisniewski, S.R., Warden, D., et al. Selecting among second-step antidepressant medication monotherapies: Predictive value of clinical, demographic, or first-step treatment features. Arch Gen Psychiatry, 65:870-881, 2008.
Wisniewski, S.R., Rush, A.J., Nierenberg, A.A., Gaynes, B.N., Warden, D., Luther, J.F., McGrath, P.J., Lavori, P.W., Thase, M.E., Fava, M., Trivedi, M.H. Can Phase III trial results of antidepressant medications be generalized to clinical practice? A STAR*D report. American Journal of Psychiatry, 166:599-607, 2009.
Rush, A.J., Warden, D., Wisniewski, S.R., Fava, M., Trivedi, M.H., Gaynes, B.N., Nierenberg, A.A. STAR*D: Revising conventional wisdom. CNS Drugs, 23:627-647, 2009.
Hedayati, S.S., Minhajuddin, A.T., Afshar, M., Toto, R.D., Trivedi, M.H., Rush, A.J. Association between major depressive episodes in patients with chronic kidney disease and initiation of dialysis, hospitalization, or death. JAMA, 303:1946-1953, 2010.
Kuk, A., Jialing, L., Rush, A.J. Recursive subsetting: A method to enhance the accuracy of early prediction of treatment outcome and to inform personalized care. Journal of Clinical Psychiatry, 71:1502-1508, 2010.
Williams, L., Rush, A.J., Koslow, S.H., Wisniewski, S.R., Cooper, N.J., Nemeroff, C.B., Schatzberg, A.F., Gordon, E. International study to predict optimized treatment for depression (iSPOT-D), a randomized clinical trial: Rationale and design. Trials, 5 January 2011; doi:10.1186/1745-6215-12-4.
Bech, P., Fava, M., Trivedi, M.H., Wisniewski, S.R., Rush, A.J. Factor structure and dimensionality of the two depression scales in STAR*D using level 1 datasets. Journal of Affective Disorders, 2011; doi:10.1016/j.jad.2011.03.011.
Rush, A.J., Trivedi, M.H., Stewart, J.W., Nierenberg, A.A., Fava, M., Kurian, B.T., Warden, D., Morris, D.W., Luther, J.F., Husain, M.M., Cook, I.A., Shelton R.C., Lesser, I.M., Kornstein, S.G., Wisniewski, S.R. Combining Medications to Enhance Depression Outcomes (CO-MED): Acute and long-term outcomes: A single-blind randomized study. American Journal of Psychiatry, 2011: doi:10.1176/appi.ajp.2011.10111645.
Trivedi, M.H., Wisniewski, S.R., Morris, D.W., Fava, M., Gollan, J.K., Warden, D., Nierenberg, A.A., Gaynes, B.N., Husain, M.M., Luther, J.F., Zisook, S., Rush, A.J. Concise Health Risk Tracking (CHRT) scale: A brief self-report and clinician-rating of suicidal risk. Journal of Clinical Psychiatry, in press.
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